Laboratory/Animal/Preclinical Studies Antitumor Effects Appetite Stimulation Analgesia Cannabinoids are a group of 21-carbon–containing terpenophenolic compounds produced uniquely by Cannabis sativa and Cannabis indica species.[1,2] These plant-derived compounds may...
Researchers find CB1 suppresses tumors, a new potential path for treatment & prevention New preclinical research shows that cannabinoid cell surface receptor CB1 plays a tumor-suppressing role in human colorectal cancer, scientists report in the Aug. 1 edition of...
Baltimore, MD: The stimulation of a specific endocannabinoid receptor by a synthetic cannabinoid agonist significantly reduces the desire for cocaine, according to preclinical data published online in the scientific journal Nature Neuroscience. Investigators at the...
Cannabinoids Cannabinoids have a favorable drug safety profile.[1-4] Unlike opioid receptors, cannabinoid receptors are not located in the brainstem areas controlling respiration; therefore, lethal overdoses due to respiratory suppression do not occur. Because...
Alzheimer’s disease (AD) is characterized by enhanced -amyloid peptide (A) deposition along with glial activation in senile plaques, selective neuronal loss, and cognitive deficits. Cannabinoids are neuroprotective agents against excitotoxicity in vitro and...