Marijuana Research
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Human Immunodeficiency Virus – HIV
In 2007, investigators at Columbia University published clinical trial data in 2007 reporting that HIV/AIDS patients who inhaled cannabis four times daily experienced “substantial … increases in food intake … with little evidence of discomfort and no impairment of cognitive performance.” They concluded, “Smoked marijuana … has a clear medical benefit in HIV-positive [subjects].
Cannabinoid Treatment: Gliomas
California Pacific Medical Center Research Institute reported that the administration of THC on human glioblastoma multiforme cell lines decreased the proliferation of malignant cells and induced cell death more rapidly than did the administration of WIN 55,212-2
Cannabinoid Treatment: Gastrointestinal Disorders
Gastrointestinal (GI) disorders, including functional bowel diseases such as irritable bowel syndrome (IBS) and inflammatory bowel diseases such as Crohn’s disease and colitis, afflict more than one in five Americans, particularly women. While some GI disorders may be...
Fibromyalgia
Subjects in the trial were administered daily doses of 2.5 to 15 mg of THC and received no other pain medication during the trial. Among those participants who completed the trial, all reported a significant reduction in daily recorded pain and electronically induced pain.
Dystonia
A small number of case reports and preclinical studies investigating the use of cannabis and cannabinoids for symptoms of dystonia are referenced in the recent scientific literature.
Cannabinoid Research: Diabetes Mellitus
A search of the scientific literature reveals no clinical investigations of cannabis for the treatment of diabetes, but does identify a small number of preclinical studies indicating that cannabinoids may modify the disease’s progression and provide symptomatic relief to those suffering from it
Cannabinoid Research: Chronic Pain
Several recent FDA-designed clinical trials indicate that inhaled marijuana can significantly alleviate neuropathic pain.
Marijuana vs Alcohol
One of the controversies in public health right now is that surrounding the use of marijuana. While it is true that marijuana is a mind altering substance, it is also true that there are legal substances that also affect the mind. One of those that comes to mind quite...
Stimulation Of Marijuana Receptor Reduces Cocaine Consumption, Study Says
Baltimore, MD: The stimulation of a specific endocannabinoid receptor by a synthetic cannabinoid agonist significantly reduces the desire for cocaine, according to preclinical data published online in the scientific journal Nature Neuroscience. Investigators at the...
ADHD And Medicinal Cannabis
Hello, my name is Tommy. I am a 33 year old man from Norway. I have ADHD and struggle with chronic panic attacks and generalized anxiety disorder. I am also a front-fighter here in Norway to get cannabis legalized as medication on prescription from your doctor, and...
HEMP vs. MARIJUANA: What's the difference?
Industrial hemp is a variety of cannabis sativa that has a long history of use in the United States. However, since the 1950s it has been lumped into the same category of marijuana, and thus the extremely versatile crop was doomed in the United States. Industrial...
Marijuana Use: Prevention of Squamous Cell Carcinoma
After adjusting for potential confounders (including smoking and alcohol drinking), 10 to 20 years of marijuana use was associated with a significantly reduced risk of HNSCC…
Cannabis use improves schizophrenia Cognition
Abstract This study examined the relationship between neuropsychological performance and three different indices of cannabis use in schizophrenia. These indices were DSM-IV lifetime abuse/dependence, frequency of use, and recency of use. Sixty males with...
Acid Reflux: Effect of Cannabinoids on the triggering of transient lower esophageal sphincter
Effect of Delta(9)-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower esophageal sphincter relaxations in dogs and humans. Background and purpose Transient lower oesophageal sphincter relaxations (TLESRs) are the main mechanism...
Effects of synthetic cannabinoid on sleep in fibromyalgia: results of a randomized controlled trial
BACKGROUND Sleep disorders affect many patients with chronic pain conditions. Cannabis has been reported by several patient populations to help sleep. We evaluated the safety and efficacy of nabilone, a synthetic cannabinoid, on sleep disturbance in fibromyalgia (FM),...
Smoked cannabis for chronic neuropathic pain: a randomized controlled trial
BACKGROUND Chronic neuropathic pain affects 1%-2% of the adult population and is often refractory to standard pharmacologic treatment. Patients with chronic pain have reported using smoked cannabis to relieve pain, improve sleep and improve mood. METHODS: Adults with...
Parkinson's Disease: Evaluation of the neuroprotective effect of cannabinoids
Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties. Abstract We have recently demonstrated that two plant-derived cannabinoids,...
Cervical Cancer: Inhibition of Cancer Cell Invasion by Cannabinoids
Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 Background Cannabinoids, in addition to having palliative benefits in cancer therapy, have been associated with anticarcinogenic effects....
Prostate Cancer: Inhibition of human tumor prostate PC-3 cell growth by cannabinoids
Inhibition of human tumor prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2 background: We have previously shown that cannabinoids induce growth inhibition and apoptosis in prostate cancer PC-3 cells, which express high...
THC effective in the treatment of schizophrenia in four case reports
1. In a letter to the editor of the Journal of Clinical Psychiatry doctors of the Rockland Psychiatric Center in Orangeburg, New York, USA, reported of four more patients with schizophrenia not responding to other medication, who improved considerably with a treatment...
Marijuana Studies & Reports
Treating Depression With Cannabinoids - Prohibitionists sometimes claim marijuana causes depression and scoff at marijuana as a treatment for depression. Here a Viennese doctor describes repeated clinical successes using oral THC to treat depression. Understanding the...
Medical Marijuana Endorsed by Leukemia and Lymphoma Society
With a vote on medical marijuana looming in the U.S. House of Representatives, the Leukemia and Lymphoma Society has adopted a formal policy position calling for removal of criminal and civil penalties for seriously ill patients using marijuana with their doctor's...
Cannabinoids induce incomplete maturation of cultured human leukemia cells
ABSTRACT Monocyte maturation markers were induced in cultured human myeloblastic ML-2 leukemia cells after treatment for 1-6 days with 0.03-30 microM delta 9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana. After a 2-day or longer treatment,...
Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation
Alzheimer's disease (AD) is characterized by enhanced -amyloid peptide (A) deposition along with glial activation in senile plaques, selective neuronal loss, and cognitive deficits. Cannabinoids are neuroprotective agents against excitotoxicity in vitro and acute...
Cannabinoid System in Neuroprotection, Raphael Mechoulam PhD
Raphael Mechoulam PhD presents explanation of cannabinoid receptors. Why would our cells have receptors specifically intended to receive cannabinoids if we were not meant to be assimilated into the body?
This is an excellent video and focuses on the scientific data to support Raphael Mechoulam PhD assertions.
Montel Williams testifies before the Los Angeles City Council: Medical Marijuana and MS
Speaking on behalf of medical marijuana patients everywhere; Montel Williams faces the Los Angeles city council as the vote to regulate dispensaries. Worth mentioning... Montel talks about the effects of butane on people with nervous system disorders - as a result I...
Stanford Study: Enhancing activity of marijuana-like chemicals in brain helps treat Parkinson's symptoms in mice
STANFORD, Calif. — Marijuana-like chemicals in the brain may point to a treatment for the debilitating condition of Parkinson’s disease. In a study published in the Feb. 8 issue of Nature, researchers from the Stanford University School of Medicine report that...
Marijuana Kills Brain Cancer Cells
The findings were published in the April 2009 issue of The Journal of Clinical Investigation. The study showed, conclusively, that THC (the active alkaloid in Cannabis) caused brain cancer cells to undergo a process called autophagy. This process causes cells to...
Cannabis and THC Improve Bladder Function in MS and Spinal Cord Injury
Preliminary results of clinical research conducted in the UK and in Switzerland show that cannabis and THC are able to reduce hyperactivity of the bladder in patients with multiple sclerosis and spinal cord injury. The Swiss study conducted at the REHAB in Basel under...
Science Daily: Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows
The active ingredient in marijuana cuts tumor growth in common lung cancer in half and significantly reduces the ability of the cancer to spread, say researchers at Harvard University who tested the chemical in both lab and mouse studies. They say this is the first...